Postdoctoral Associate – LbL Nanoparticle Systems for Biofilm Targeting against Antimicrobial Resistance:
This opening is located at the MIT-Singapore SMART Program at the CREATE Center Campus at the (1 CREATE Way), NUS, Singapore, and is in collaboration with efforts at the Nanyang Technological University. The P.T. Hammond research lab at SMART-MIT, in collaboration with the M.B.E. Chan Lab at NTU, Singapore, will develop electrostatically assembled nanolayered particles for the targeting of infections in biofilms. We seek to investigate these systems with the ultimate intent of developing promising systems that can be translated to meaningful clinical applications. The position requires a highly motivated and independent researcher with strong biomaterials background, and experience with polymer synthesis and characterization, cell culture and biological laboratory know-how and the ability to work collaboratively and manage interactions with faculty and a broad range of senior and junior research collaborators. Experience with biological assays, confocal microscopy, or work with bacteria and/or microbiology background is considered favorable but not required. Interested parties must be willing to live and work in Singapore throughout the project period.
Postdoctoral Associate – Immune monitoring with cell-sampling microneedles
A postdoctoral research position is available jointly supervised in the labs of Darrell Irvine and Paula Hammond in the Koch Institute for Integrative Cancer Research at MIT, for translational studies of microneedle patches designed to enable non-invasive sampling of cells and fluids from skin (see Mandal et al. Sci. Transl. Med. 10(467) eaar2227 2018; http://doi.org/10.1126/scitranslmed.aar2227). This project will focus on the application and further development of our microneedle sampling system to analysis of immune responses to tuberculosis and TB vaccines in small and large animal models in collaboration with the laboratory of Sarah Fortune at Harvard University, and translation toward human skin sampling. The appointment will be annual with renewal based on satisfactory progress and continued funding support. Candidates with strong expertise in cellular and/or clinical immunology, vaccine immunology, or bioengineering (particularly with microneedle technology background) are particularly encouraged to apply. Interested candidates should send a c.v. with the names of 3 references to Darrell Irvine (djirvine[at]mit.edu).