Publications (Recent)

2018 - 2019


Correa, S., Boehnke, N., Deiss-Yehiely, E., & Hammond, P. T. (2019). Solution Conditions Tune and Optimize Loading of Therapeutic Polyelectrolytes into Layer-by-Layer Functionalized Liposomes. ACS Nano.


B. C. Geiger, S. Wang, R. F. Padera Jr., A. J. Grodzinsky, P. T. Hammond. Cartilage penetrating nanocarriers improve delivery and efficacy of growth factor treatment of osteoarthritisScience Translational Medicine, 2018, 10.

A. Mandal, A. V. Boopathy, L. K. W. Lam, K. D. Moynihan, M. E. Welch, N. R. Bennett, M. E. Turvey, N. Thai, J. H. Van, J. C. Love, P. T. Hammond, D. J. Irvine. Cell and fluid sampling microneedle patches for monitoring skin-resident immunity. Science Translational Medicine, 2018, 10.

Y. He, C. Hong, J. Li, M. T. Howard, Y. Li, M. E. Turvey, D. S. S. M. Uppu, J. R. Martin, K. Zhang, D. J. Irvine, P. T. Hammond. Synthetic Charge-Invertible Polymer for Rapid and Complete Implantation of Layer-by-Layer Microneedle Drug Films for Enhanced Transdermal Vaccination. ACS Nano 2018, 12,  10272-10280.

K. Zhang, M. B. McDonald, I. E. A. Genina, P. T. Hammond. A Highly Conductive and Mechanically Robust OH Conducting Membrane for Alkaline Water Electrolysis. Chemistry of Materials 2018, 30, 6420-6430.

Y. Krishnan, H. A. Rees, C. P. Rossitto, S-.E. Kim, H. K. Hung, E. H. Frank, B. D. Olsen, D. R. Liu, and P. T. Hammond, Green fluorescent proteins engineered for cartilage-targeted drug delivery: Insights for transport into highly charged avascular tissues, Biomaterials 2018, 183, 218-233.

C. Wu, J. Li, W. Wang, and P. T. Hammond, Rationally designed polycationic carriers for potent polymeric siRNA-mediated gene silencing, ACS Nano 2018, 12, 6504-6514.

E. S. Kang, Y-. T. Kim, Y-. S. Ko, N. H. Kim, G. Cho, Y. H. Huh, J-. H. Kim, J. Nam, T. T. Thach, D. Youn, Y. D. Kim, W. S. Yun, W. F. DeGrado, S. Y. Kim, P. T. Hammond, J. Lee, Y-. U. Kwon, D-. H. Ha, and Y. H. Kim, Peptide-programmable nanoparticle superstructures with tailored electrocatalytic activity, ACS Nano 2018, 12, 6554-6562.

B. C. Geiger, A. J. Grodzinsky, and P. T. Hammond, Designing drug delivery systems for articular jointsChemical Engineering Progress 2018, 114, 46-51.

F. C. Lam, S. W. Morton, J. Wyckoff, T. V. Han, M. K. Hwang, A. Maffa, E. Balkanska-Sinclair, M. B. Yaffe, S. R. Floyd, and P. T. Hammond, Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles, Nature Communications 2018, 9, 1991.

M. McDonald and P. T. Hammond, Efficient Transport Networks in a Dual Electron/Lithium-Conducting Polymeric Composite for Electrochemical Applications, ACS Applied Materials & Interfaces 2018, 10, 15681-15690.

J. Li, C. Wu, W. Wang, Y. He, E. Elkayam, L. Joshua-Tor, and P. T. Hammond, Structurally Modulated Codelivery of siRNA and Argonaute 2 for Enhanced RNA Interference, Proceedings of the National Academy of Science 2018, 115, 2696-2705.

E.C. Dreaden, Y.W. Kong, M.A. Quadir, S. Correa, L. Suárez-López, A.E. Barberio, M.K. Hwang, A.C. Shi, B.Oberlton, P.N. Gallagher, K.E. Shopsowitz, K.M. Elias, M.B. Yaffe, and P. T. Hammond, RNA-Peptide Nanoplexes Drug DNA Damage Pathways in High-Grade Serous Ovarian Tumors, Bioengineering & Translational Medicine 2018, 3, 26-36.

W. Wang and P.T. Hammond, Hydrolysis resistant functional polypeptide scaffold for biomaterials, Polymer Chemistry 2018, 9, 346-351.



E.C. Dreaden, Y.W. Kong, M.A. Quadir, S. Correa, L. Suárez-López, A.E. Barberio, M.K. Hwang, A.C. Shi, B.Oberlton, P.N. Gallagher, K.E. Shopsowitz, K.M. Elias, M.B. Yaffe, and P. T. Hammond, RNA-Peptide Nanoplexes Drug DNA Damage Pathways in High-Grade Serous Ovarian Tumors, Bioengineering & Translational Medicine 2017, in press.

W. Wang and P.T. Hammond, Hydrolysis resistant functional polypeptide scaffold for biomaterials, Polymer Chemistry 2017, in press.

Y. He*, J. Li*, M. E. Turvey, M. T. Funkenbusch, C. Hong, D. S. S. M. Uppu, H. He, D. J. Irvine, P. T. Hammond, Synthetic lift-off polymer beneath layer-by-layer films for surface-mediated drug delivery. ACS Macro Letters 2017, 6, 1320-1324. *co-first author

M. B. McDonald, M. Freund, P. T. Hammond, Catalytic, Conductive Bipolar Membrane Interfaces via Layer-by-Layer Deposition for the Design of Membrane-Integrated Artificial Photosynthesis Systems. ChemSusChem 2017, 10, 4599-4609.

J. Li*, Y. He*, W. Wang, C. Wu, C. Hong, P. T. Hammond, Polyamine-mediated stoichiometric assembly of ribonucleoproteins for enhanced mRNA delivery. Angewandte Chemie International Edition 2017, 56, 13709-13712. *co-first author

L. Gu, J. Z. Deng, S. Roy, P. T. Hammond, A Combination RNAi-Chemotherapy Layer-by-Layer Nanoparticle for Systemic Targeting of KRAS/P53 with Cisplatin to Treat Non-small Cell Lung Cancer. Clinical Cancer Research 2017, 23, 7312-7323.

F. Tian, J. Kanka, F. Yang, J. Min, P. T. Hammond, Role of silica nanoparticles in monitoring and prolonging release of drug-eluting polyelectolyte coatings using long-period fiber grating platform. Sensors and Actuators B: Chemical 2017, 252, 831-839.

C. V. Amanchukwu, H.-H. Chang, P. T. Hammond, Influence of Ammonium Salts on Discharge and Charge of Li–O2 Batteries. The Journal of Physical Chemistry C 2017, 121, 17671–17681.

P. T. Hammond, Nano tools pave the way to new solutions in infectious disease. ACS Infectious Diseases 2017, 3, 554-558.

M. Tulodziecki, G. M. Leverick, C. V. Amanchukwu, Y. Katayama, D. G. Kwabi, F. Barde, P. T. Hammond, Y. Shao-Horn, The role of iodide in the formation of lithium hydroxide in lithium-oxygen batteries. Energy and Environmental Science 2017, 10, 1828-1842.

M. T. Klug, N.-M. Dorval Courchesne, Y. E. Lee, D. S. Yun, J. Qi, N. C. Heldman, P. T. Hammond, N. X. Fang, A. M. Belcher, Mediated Growth of Zinc Chalcogen Shells on Gold Nanoparticles by Free-Base Amino Acids. Chemistry of Materials 2017, 29, 6993-7001.

A.V. Boopathy, A. Mandal, D. W. Kulp, S. Kumari, W. Wang, Y. He, T. Tokatlian, W. R. Schief, P. T. Hammond, D. J. Irvine, Sustained delivery of a HIV subunit vaccine using silk microneedle skin patches. The Journal of Immunology 2017, 198(1 Supplement), 225.22.

S. A. Castleberry, M. A. Quadir, M. A. Sharkh, K. E. Shopsowitz, P. T. Hammond, Polymer conjugated retinoids for controlled transdermal delivery. Journal of Controlled Release 2017, 262, 1-9.

S. Akbari, T. Pirbodaghi, R. D. Kamm, P. T. Hammond, A versatile microfluidic device for high throughput production of microparticles and cell microencapsulation. Lab on a Chip 2017, 17. 2067-2075.

M. A. Quadir, S. W. Morton, L. B. Mensah, K. Shopsowitz, J. Dobbelaar, N. Effenberger, P. T. Hammond, Ligand-decorated click polypeptide derived nanoparticles for targeted drug delivery applications. Nanomedicine: Nanotechnology, Biology and Medicine 2017, 13, 1797-1808.

J. Li, W. Wang, Y. He, Y. Li, E. Z. Yan, K. Zhang, D. J. Irvine, P. T. Hammond, Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery. ACS Nano 2017, 11, 2531-2544.

M.-H. Park, E. Reátegui, W. Li, S. N. Tessier, K. H. K. Wong, A. E. Jensen, V. Thapar, D. Ting, M. Toner, S. L. Stott, P. T. Hammond, Enhanced Isolation and Release of Circulating Tumor Cells Using Nanoparticle Binding and Ligand Exchange in a Microfluidic Chip. Journal of the American Chemical Society 2017, 139, 2741-2749.

A. Khademhosseini, W. W. C. Chan, M. Chhowalla, S. C. Glotzer, Y. Gogotsi, J. H. Hafner, P. T. Hammond, M. C. Hersam, A. Javey, C. R. Kagan, N. A. Kotov, S.-T. Lee, Y. Li, H. Möhwald, P. A. Mulvaney, A. E. Nel, W. J. Parak, R. M. Penner, A. L. Rogach, R. E. Schaak, M. M. Stevens, A. T. S. Wee, J. Brinker, X. Chen, L. Chi, M. Crommie, C. Dekker, O. Farokhzad, C. Gerber, D. S. Ginger, D. J. Irvine, L. L. Kiessling, K. Kostarelos, C. Landes, T. Lee, G. J. Leggett, X.-J. Liang, L. Liz-Marzán, J. Millstone, T. W. Odom, A. Ozcan, M. Prato, C. N. R. Rao, M. J. Sailor, E. Weiss, P. S. Weiss, Nanoscience and Nanotechnology Cross Borders. ACS Nano 2017, 11, 1123-1126.



C. V. Amanchukwu, H. H. Chang, M. Gauthier, S. Feng, T. P. Batcho, P. T. Hammond, A One Electron Process in a Gel Polymer Electrolyte Li-O2 Battery, Chemistry of Materials 2016, in press.

C. V. Amanchukwu, M. Gauthier, T. P. Batcho, C. Symister, Y. Shao-Horn, J. M. D’Arcy, P. T. Hammond, Evaluation and Stability of PEDOT Polymer Electrodes for Li–O2 Batteries, The Journal of Physical Chemistry Letters 2016, 7, 3770.

S. Correa, E. C. Dreaden, L. Gu, P. T. Hammond, Engineering Nanolayered Particles for Modular Drug Delivery, Journal of Controlled Release 2016, in press.

C. Wu, K. E. Shopsowitz, P. T. Hammond, Engineering Periodic shRNA for Enhanced Silencing Efficacy, Molecular Therapy 2016, 24, 1070.

J. Min, K. Y. Choi, E. C. Dreaden, R. F. Padera, R. D. Braatz, M. Spector, P. T. Hammond, Designer Dual Therapy Nanolayered Implant Coatings Eradicate Biofilms and Accelerate Bone Tissue Repair, ACS Nano 2016, 10, 4441.

X. Dang, L. Gu, J. Qi, S. Correa, G. Zhang, A. M. Belcher, P. T. Hammond, Layer-by-Layer Assembled Fluorescent Probes in the second Near-Infrared Window for Systemic Delivery and Detection of Ovarian Cancer, Proceedings of the National Academy of Sciences 2016, 113, 5179.

S. A. Castleberry, A. Golberg, M. A. Sharkh, S. Khan, B. D. Almquist, W. G. Austen Jr, M. L. Yarmush, P. T. Hammond, Nanolayered siRNA Delivery Platforms for Local Silencing of CTGF Reduce Cutaneous Scar Contraction in Third-Degree Burns, Biomaterials 2016, 95, 22.

S. Correa, K. Y. Choi, E. C. Dreaden, K. Renggli, A. Shi, L. Gu, K. E. Shopsowitz, M. A. Quadir, E. Ben-Akiva, P. T. Hammond, Highly Scalable, Closed-Loop Synthesis of Drug-Loaded, Layer-by-Layer Nanoparticles, Advanced Functional Materials 2016, 26, 991.

S. A. Castleberry, B. D. Almquist, W. Li, T. Reis, J. Chow, S. Mayner, P. T. Hammond, Self-Assembled Wound Dressings Silence MMP-9 and Improve Diabetic Wound Healing In Vivo, Advanced Materials 2016, 28, 1809.

K. E. Shopsowitz, C. Wu, G. Liu, E. C. Dreaden, P. T. Hammond, Periodic-shRNA Molecules are Capable of Gene Silencing, Cytotoxicity and Innate Immune Activation in Cancer Cells, Nucleic Acids Research 2016, 44, 545.

Y. H. Roh, J. Z. Deng, E. C. Dreaden, J. H. Park, D. S. Yun, K. E. Shopsowitz, P. T. Hammond, A Multi-RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs, Angewandte Chemie International Edition 2016, 55, 3347.

P. T. Hammond, Shooting for the Moon: Nanoscale Approaches to Cancer, ACS Nano 2016, 10, 1711.

A. Jaklenec, A. C. Anselmo, J. Hong, A. J. Vegas, M. Kozminsky, R. Langer, P. T. Hammond, D. G. Anderson, High Throughput Layer-by-Layer Films for Extracting Film Forming Parameters and Modulating Film Interactions with Cells, ACS Applied Materials & Interfaces 2016, 8, 2255.

T.C. Reis, S. Castleberry, A.M.B. Rego, A. Aguiar-Ricardo, P.T. Hammond, Three-Dimensional Multilayered Fibrous Constructs for Wound Healing Applications, Biomaterials Science 2016, 4, 319.

A.G. Bajpayee, M.A. Quadir, P.T. Hammond, A.J. Grodzinsky, Charge Based Intra-Cartilage Delivery of Single Dose Dexamethasone Using Avidin Nano-Carriers Suppresses Cytokine-induced Catabolism Long Term, Osteoarthritis and Cartilage 2016, 24, 71.