Postdoctoral Associate – LbL Nanoparticle Systems: This position in the Hammond lab, at the Koch Institute of Integrative Cancer Research at MIT, will be filled by a biomedical engineer, or M.D./PhD with strong materials science, biological and/or biomedical background and expertise in animal studies and histology. Background in polymeric biomaterials is especially encouraged though not essential. This postdoctoral associate will examine the pharmacokinetics, biodistribution and tumor targeting efficacy of siRNA targeted against a unique set of synergistic genetic targets, with and without combinations of chemotherapy drug, to address advanced serous ovarian cancer. Collaborations within the Koch Institute Marble Center on Nanomedicine, including those involving combination therapy nanoparticle systems, theranostic systems, and the potential to explore immuno-oncology applications of nanoparticle systems will be examined. Simple and more advanced animal models will be used to new delivery systems as well as new therapeutic combinations made possible with layer-by-layer nanoparticle technologies and related approaches.
Postdoctoral Associate – Bone Tissue Regeneration for Craniomaxillofacial Repair: In this work, we seek to release potent bioactive agents in physiologically appropriate dose levels from degradable scaffolds to recruit native bone precursor cells to the healing site, and achieve full integration of new and native bone. This position in the Hammond lab, at the Koch Institute of Integrative Cancer Research, at MIT seeks a biomaterials scientist or engineer, chemical engineer, or materials scientist with a strong background in biomaterials development and the ability to integrate concepts from polymer science, biology, and physiology to address materials design for this application. Previous experience with animal studies and/or strong interest in engaging with animal models preferred. Requires ability to engage with Boston area clinical and industrial experts.