Ki Young Choi

 

Postdoctoral Researcher

Precise Nanomedicine for Targeted Delivery and Controlled Release of Gene and Chemotherapeutics

Despite remarkable advances in chemotherapeutics, the use of conventional chemotherapy is still limited due to the random tissue-distribution of cytotoxic drugs following systemic administration, which can cause non-specific toxicity to normal tissues. In an effort to reduce toxicity to normal tissues and to improve therapeutic efficacy of the therapeutics, Dr. Choi’s current research is focused on the development of potent nanomedicine systems based on biomacromolecules (e.g. hyaluronan, dextran or glycol chitosan) for precise delivery of chemo- and gene-therapeutics to target sites as well as for disease-specific and stimuli-responsive release of the therapeutics. The precise nanomedicine will be achieved by use of multiple techniques including nano- and polymer-engineering, layer-by-layer assembly, bioconjugation, drug formulation and in vitro/in vivo multi-modality imaging techniques. Click here to see a list of Dr. Choi's publications

Email: kychoi @ mit.edu